• Associations of inner retinal layers with risk of incident dementia: An individual participant data analysis of four prospective cohort studies 

      van der Heide, Frank C. T.; Khawaja, Anthony; Berendschot, Tos T. J. M.; Littlejohns, Thomas J.; Kuźma, Elżbieta; Luben, Robert; Patel, Praveen J.; Foster, Paul J.; Bertelsen, Geir; von Hanno, Therese; Johnsen, Bente; Schirmer, Henrik; Rebouças, Sara C. L.; Grasset, Leslie; Delcourt, Cécile; Helmer, Catherine; Stehouwer, Coen D. A. (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-08-08)
      INTRODUCTION - Our main objective was to investigate whether retinal neurodegeneration, estimated from lower thickness of inner retinal layers, was associated with incident all-cause dementia and Alzheimer's disease (AD).<p> <p>METHODS - We performed an individual participant data meta-analysis using unpublished data from four prospective cohort studies with a total of 69,955 participants (n = ...
    • The decreasing prevalence of nonrefractive visual impairment in older Europeans: a meta-analysis of published and unpublished data 

      Delcourt, Cécile; Le Goff, Mélanie; von Hanno, Therese; Mirshahi, Alireza; Khawaja, Anthony P.; Verhoeven, Virginie J.M.; Hogg, Ruth E.; Anastosopoulos, Eleftherios; Cachulo, Maria Luz; Höhn, René; Wolfram, Christian; Bron, Alain; Miotto, Stefania; Carrière, Isabelle; Colijn, Johanna M.; Buitendijk, Gabriëlle H.S.; Evans, Jennifer; Nitsch, Dorothea; Founti, Panayiota; Yip, Jennifer L.Y.; Pfeiffer, Norbert; Creuzot-Garcher, Catherine; Silva, Rufino; Piermarocchi, Stefano; Topouzis, Fotis; Bertelsen, Geir; Foster, Paul J.; Fletcher, Astrid; Klaver, Caroline C.W.; Korobelnik, Jean-François (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-03-13)
      <p><i>Topic</i>: To estimate the prevalence of nonrefractive visual impairment and blindness in European persons 55 years of age and older.</p> <p><i>Clinical Relevance</i>: Few visual impairment and blindness prevalence estimates are available for the European population. In addition, many of the data collected in European population-based studies currently are unpublished and have not been ...
    • Macular Layer Thickness and Effect of BMI, Body Fat, and Traditional Cardiovascular Risk Factors: The Tromsø Study 

      von Hanno, Therese; Hareide, Live Lund; Småbrekke, Lars; Morseth, Bente; Sneve, Monica; Erke, Maja Gran; Mathiesen, Ellisiv B.; Bertelsen, Geir (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-08-12)
      PURPOSE. The purpose of this study was to investigate associations between cardiovascular risk factors and the thickness of retinal nerve fiber layer (RNFL), ganglion cell-inner plexiform layer (GCIPL), and outer retina layers (ORL).<p> <p>METHODS. In this population-based study, we included participants from the Tromsø Study: Tromsø6 (2007 to 2008) and Tromsø7 (2015 to 2016). Persons with ...
    • Trajectories of recall memory as predictive of hearing impairment: A longitudinal cohort study 

      Maharani, Asri; Dawes, Piers; Nazroo, James; Tampubolon, Gindo; Pendleton, Neil; Bertelsen, Geir; Cosh, Suzanne; Cougnard-Grégoire, Audrey; Delcourt, Cécile; Constantinidou, Fofi; Goedegebure, Andre; Helmer, Catherine; Arfan Ikram, M; Klaver, Caroline C.W.; Leroi, Iracema; Meester-Smor, Magda; Nae, Virginie; Oosterloo, Neelke; Schirmer, Henrik; Tiemeier, Henning; von Hanno, Therese (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-06-18)
      <i>Objectives</i> - Accumulating evidence points to a relationship between hearing function and cognitive ability in later life. However, the exact mechanisms of this relationship are still unclear. This study aimed to characterise latent cognitive trajectories in recall memory and identify their association with subsequent risk of hearing impairment.<p> <p><i>Methods</i> - We analysed data from ...